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It allows for a slow, steady delivery of hormones, rather than constant fluctuation

1,2,6 The resultant abnormal erythropoiesis can trigger other notable abnormal laboratory findings, such as decreased haptoglobin levels, high lactate dehydrogenase levels, and elevated reticulocyte count

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However, the dominant opinion is to integrate B12 as part of rational and healthy nutrition to ensure proper function of the immune system

The approval of recombinant human erythropoietin in 1989 drastically shifted the treatment of renal anemia