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Tests carried out on mice in order to determine LD50 as well as with the purpose of obtaining data about acute, sub chronic and chronic toxicity have been unsuccessful as this peptide applied intravenously or intraperitoneally in a broad dose range from 10 ng to 100 mg/kg of body weight, did not induce any toxic changes

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Engrailed 2 deficiency and chronic stress alter avoidance and motivation behaviors

However, several weeks is the upper limit for room temperature viability

Contamination during peptide reconstitution does not just reduce potency

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