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and (v) final sulfation, where desulfoglucosinolate sulfotransferases catalyze sulfation, converting desulfoglucosinolates into bioactive GSLs [24,68,69,70]

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Additionally, BSO increased NGF levels and activated the NGF/TrkA/Akt pathway in striatal neurons

Subsequently, the reaction mixture was precipitated into a copious amount of chilled diethyl ether, filtered to separate the solid product, washed thoroughly with diethyl ether three consecutive times, and finally dried under vacuum until a constant weight was achieved (8.74 g, 0.45 mmol, 90% yield)

Moreover, when reacting with free radicals, intracellular lipids can cause oxidative damage and even cell death owing to the production of lipid peroxides

We have also reported that NAC does not interfere with the myeloablative effect of Bu in vitro or in animal models, and that it can be considered for SOS prophylaxis during Bu conditioning 21