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In contrast, chronic conditions involve complex interactions of fibrosis, inflammation, and progressive cellular damage, fundamentally impairing regeneration due to disrupted tissue architecture

doi: 10.1111/cpr.13638 116 ChenSHanHSunXZhouGZhouQLiZ

As a result, the release of IL-1, IL-6 and TNF- in the colon is reduced, the expression of tight junction proteins is increased, the integrity of the intestinal barrier is maintained, and the symptoms of UC mice are improved