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Garlic and SAC were recently shown to inhibit activation of NF-B in different cell types, including endothelial cells, so they can be likely to inhibit atherosclerosis and hypertension by suppressing the expression of NF-B and lowering ROS concentration

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Core proteins involved in fatty acid uptake and phospholipid hydroperoxide synthesis, including CD36, ACSL4, and NADPH-cytochrome P450 reductase (POR), have been validated as drivers of ferroptosis (Fig

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