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Zhang JY, Xie B, Barba H, Nadeem U, Movahedan A, Deng N et al (2022) Absence of gut microbiota is associated with RPE/choroid transcriptomic changes related to age-related macular degeneration pathobiology and decreased choroidal neovascularization

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The risk of heart diseasemainly hypertension and arterial diseaseincreased steadily by 4% per year in children and adults, according to a recent large case-controlled study (Zhang L et al, JAMA Psychiatry 2024;81(2):178187)

National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention

In addition, KG is a cofactor for the Fe(II)/2-oxoglutarate-dependent dioxygenases (OGDD), including Jumonji-domain (JMJC)-containing histone demethylases, ten-eleven translocation (TET) DNA demethylases and hypoxia-inducible factors (HIF)-prolyl hydroxylases (PHD) essential for HIF-hydroxylation and consequent degradation [70]