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Acta Vet Scand (2004) 45(1-2):11928

reported a pH-responsive ZIF-67 dual-delivery system in which pretilachlor was encapsulated within the framework and the safener 4-(dichloroacetyl)-1-oxa-4-azospiro[4,5]decane (AD-67) was assembled on the particle surface to achieve sequential release under mildly acidic conditions ( Figure 8 )