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Vitamin B12, an essential nutrient found predominantly in animal products, plays a crucial role in nerve function, red blood cell formation, and DNA synthesis

(10)Fmoc-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin (10) Preparation of Fmoc-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin (9)Fmoc-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin(20DMF)5203DMF3DMF2Fmoc-Gly-OH0.7gDIEA0.4mlTBTU0.56gHOBT0.2gDMF10ml1.53DMF3DMF2Fmoc-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin In the Fmoc-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin in step (9), add a decapping reagent (20% piperidine in DMF) , reacted at room temperature for 5 minutes, drained, added decapping agent and reacted at room temperature for 20 minutes, washed 3 times with isopropanol, washed 3 times with DMF, washed 2 times with distilled DMF, drained, added Fmoc-Gly-OH0

Research indicates that the specific molecular configuration of the B12 molecule has minimal or no impact on the body's conversion process once ingested

Malavasi F, Deaglio S, Funaro A, Ferrero E, Horenstein AL, Ortolan E, et al

Consistency is important for managing vitamin B12 deficiency, so try to stick to the prescribed schedule as closely as possible

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