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GOT2 catalyzes the conversion of oxaloacetate to aspartate in the mitochondria and has been shown to be an important regulator of cancer metabolism (13)

In addition to the production of ROS localized in regions of infection, PMN, in combination with T lymphocytes, use a variety of cytotoxic mechanisms to fight infection, including the release of antimicrobial peptides and the expulsion of their nuclear contents to form extracellular traps (Mayadas et al