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Description

11beta-hsd1 inhibition by rl-118 promotes autophagy and correlates with reduced oxidative stress and inflammation, enhancing cognitive performance in samp8 mouse model

Their favorable safety profile, extended into infants, supports early clinical application

W., Huang, K

JoVE (J Vis Exp) (153):e60335 Fabre ML, Arras PN, Masson T, Pidre ML, Romanowski V (2020) Baculovirus-derived vectors for immunization and therapeutic applications