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It has been shown, that many types of tumors express both the ligand - HGF and receptor - c-Met

Interestingly, the same pattern of autophagy induction was also seen in uninfected C6/36 cells, as well in SF9 cells, suggesting the mode of action of these drugs is independent of Wolbachia infection

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Stimulation of the MEK5/Erk5 axis by IGF-IR bypasses the inhibition of BRAF, MEK1/2, and Erk1/2 [130]

7.2 Mitophagy and inflammation Mitophagy is the selective degradation of mitochondria by autophagosome, which prevents an excessive inflammatory response

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