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The significant parameters controlling GT productivity by the potent fungus were optimized by the face-centered central composite design (FCCD), to assess the variables mutual interactions, as represented by 5 levels low 1, medium 0, and high + 1, with center point repeated 6 times

Free fatty acid receptor 1 plays a pivotal role in airway contraction and ASM cell proliferation, as observed in a study demonstrating that FFAR1 promotes ASM cell proliferation through MEK/ERK and PI3K/Akt signaling pathway (308)

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Levey AS, Coresh J, Greene T, Stevens LA, Zhang Y, Hendriksen S et al (2006) Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate