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Preclinical studies have not reported significant adverse effects

Another common question: Why am I only taking this 5 days a week? or "why must I take breaks periodically?" Its a smart strategy, not a mistake

doi: 10.1016/j.cccn.2005.04.029 50 Soetekouw PMWRVrekenPElvingLDJanssenAJvan der VeenYBleijenbergGet al

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When insulin levels are elevated, such as after a carbohydrate-rich meal, insulin tends to dominate receptor binding