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In a controlled human study, CJC-1295 produced sustained, dose-dependent increases in GH and IGF-1 in healthy adults and was reported as generally well tolerated in that setting

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It has been reported that the N-terminus of DAT is essential for protein kinase C-mediated phosphorylation on serine residues [67], and the first 22 amino acids from the N-terminus of DAT eliminate phosphorylation of DAT in response to PKC activation [44]