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Intracellular proteolytic processing of precursor polypeptides is an essential step in the maturation of many proteins such as plasma proteins, hormones, neuropeptides, and growth factors 331

The X-linked histone demethylase Kdm6a in CD4+ T lymphocytes modulates autoimmunity

However, in line with our previous findings, indicating another factor capable of catalyzing disulfide bond formation in the periplasm, the dsbA lysate was still significantly faster than a buffer control (Fig