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most of the herbal extracts and concentrated polyphenols may aggravate them currently which makes it difficult to support care and adherence to medication periods (207)

discovered that RPA1 can undergo crotonylation at K88, K379, and K595, and the RPA1 modified by crotonylation is more likely to bind to damaged single-stranded DNA and HR proteins, thereby promoting DNA damage repair and the survival of tumor cells