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Oxidative stress (101), inflammation, endothelial dysfunction and impaired lipid metabolism (102) may be associated with the mechanism behind copper deficiency-induced atherosclerosis

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Low glutathione levels are associated with chronic inflammatory conditions, including depression 4, type 2 diabetes 7 8, Alzheimers disease 9, cognitive decline 10, and autoimmune disorders 11

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Combining other metabolic conditions, such as diabetes and obesity, with an imbalanced fat metabolismwhich is a pro-atherosclerotic factormay significantly increase the risk of cardiovascular disease (CVD), especially in people with CKD (145)

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