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Study Designs The wide range of background therapies and study population characteristics at baseline in SURPASS-15 reflect the continuum of T2D disease (with mean disease duration ranging from 4.7 to 13.3 years) and treatment (including monotherapy, combination oral therapy and insulin)

Moreover, advancing personalized medicine in AD will require the incorporation of pharmacogenomic profiling to assess individual responses to natural compounds

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A further consideration is the use of acid-suppressing medicines

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