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Cocaine neurotoxicity and neurological damage stem from several mechanisms, including mitochondrial dysfunction (Poon et al., 2007), neuroinflammation (Moran et al., 2005), and autophagy ( 3.1 Vascular effects of cocaine Cocaine impairs vascular function by causing vasoconstriction, reducing cerebral blood flow, and decreasing tissue oxygenation

Oxidative Medicine and Cellular Longevity, 2021 , Article 1987588

Apolipoprotein CIII-induced THP-1 cell adhesion to endothelial cells involves pertussis toxin-sensitive G protein- and protein kinase C-mediated nuclear factor-B activation

Plasma and cerebrospinal fluid tryptophan in multiple sclerosis and degenerative diseases

Right now were working on an computer application to try and streamline the MSIDS diagnostic and treatment process for patients and physicians

J Cell Biol , 219 , e202001147 (2020)