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It has been found that during postoperative incisional pain, activation of BLT1 receptors by LTB 4 exacerbates pain responses by promoting local infiltration of inflammatory monocytes and cytokine production (IL-6, IL-1, and TNF-) [218]

Mechanisms of the Trx system involved in autophagy in different diseases The autophagic process comprises four mechanistically distinct phases: Autophagosome nucleation/maturation, cargo sequestration, autolysosomal fusion and lysosomal degradation (106,107)

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