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Data were log 10 transformed if they were non-normally distributed and/or heteroscedastic

The mechanism involves restoration of NAD+ levels in aging muscle tissue, which reverses muscle stem cell senescence and dysfunction

Follow all applicable local regulations regarding research compounds.

J Biol Chem

While they are safe for many people, its important to consult with a healthcare provider to determine if they are appropriate for you, especially if you have any underlying health conditions or are on certain medications.

Approach Phase 2b trial arm Duration 24 weeks Review Point Week 12 and 24 Notes METAOD006 (OPTIONS) used 24 weeks at oral doses 0.25, 0.5, or 1 mg/day in 502 obese adults