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Metabolic Theory According to the metabolic theory, noise exposure could lead to extensive metabolic changes in the auditory system

State Lyophilized (powder) Storage 35.6-46.4F (2-8C) refrigerator Duration Several months

Statements Author contributions HD: Methodology, Resources, Writingoriginal draft, Writingreview and editing

Following gut immune activation, activated immune cells and effector molecules such as cytokines [e.g., Interleukin-17 (IL-17), Tumor Necrosis Factor-alpha (TNF- )] can promote local inflammatory responses, alter the oral microecological environment, and either inhibit or promote the growth of specific microbial communities, playing a pivotal role in the regulation of oral microbiota (Nagao et al., 2022)

On the other hand, classical methods that detect the changes of properties for the overall system cannot provide accurate information on what occurred among individual components in the complex system

Glial cells and immature neurons are more susceptible to the free form of bilirubin than mature ones according to several investigations [21]