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doi: 10.3389/fimmu.2018.02658 Received 03 September 2018 Accepted 29 October 2018 Published 16 November 2018 Volume 9 - 2018 Edited by Jos Carlos Crispn, Instituto Nacional de Ciencias Mdicas y Nutricin Salvador Zubirn (INCMNSZ), Mexico Reviewed by Pier Luigi Meroni, Istituto Auxologico Italiano (IRCCS), Italy

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Inhibition of ODC1 with difluoromethyl ornithine (DFMO) reduced the production of toxic byproducts and improved memory performance in APP/PS1 mice, a widely used transgenic model of AD