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Potential pharmacological properties of triterpene derivatives of ursolic acid

In summary, ferroptosis represents not merely an additional mode of cell death but a conceptual framework that links metabolic dysregulation, oxidative injury, and inflammation in cardiovascular disease

Similar to bacteria, systemic viral infections often lead to marked expression of proinflammatory cytokines and vascular complications, such as thrombosis and/or hypoxemia (Ishiguro et al., 2019

Platelet-derived growth factor receptor (PDGFR) is another RTK that is overexpressed in Schwann cells derived from neurofibromas 29 and MPNSTs, 30 and the expression levels of the c-met RTK proto-oncogene product and its ligand hepatocyte growth factor (HGF) correlate with disease progression

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Issa, F.A., Mock, A.F., Sagasti, A