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Lovatt M, Adnan K, Kocaba V, Dirisamer M, Peh GSL, Mehta JS

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10.1016/j.intimp.2022.109162 212 RamakrishnanM.ArivalaganJ.SatishL.MohanM.Samuel Selvan ChristyrajJ

2) For large volume of supernatant, concentrate the proteins by ammonium sulphate precipitation, dialyze it against 1 PBS at 4C before applying it onto the column

In recent years, IDH inhibitors targeting IDH mutants, including ivosidenib and enasidenib (Table 1), have been approved by the Food and Drug Administration to be used in patients with IDH1 or IDH2 mutant recurrent or refractory AML, respectively (Kim, 2017

The increasing prevalence of these disorders necessitates rapid therapeutic development