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ChlebowskiRTBlackburnGLThomsonCANixonDWShapiroAHoyMKet al

10.1016/j.clinph.2014.05.021 Clin

This cycle is shown below, taken from a 2005 AJKD paper by Humphreys et al

Even more intense stimulation can disrupt the cellular organization of the sensory epithelium, producing profound damage directly or indirectly via potassium exposure of the HC basal poles