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This helps researchers move from compound-specific review into broader pathway comparison without leaving the core research archive

A better understanding of the multiple molecular mechanisms involved in the cellular action of fumaric acid esters (FAEs) will help to adapt and to further improve the use of such small molecules for the treatment of psoriasis and other chronic inflammatory diseases (6)

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On the first day, bilateral vertebral arteries were irreversibly electro-cauterized under anaesthesia with sevoflurane (a mixture of 3.5% sevoflurane in 33% O 2 and 66% N 2 O)

If the phenotypes of the mutants can be successfully restored to wild type, this will confirm that only the correct genes have been deleted and further validate the specific phenotypes ascribed to each GDH mutant

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