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Although controversy remains over whether KD should be used to treat cancer, therapies that slow or stop cancer growth in early stages, use a broad-spectrum approach, target many signaling pathways, prevent cancer comorbidities such as cachexia and obesity, and have fewer adverse effects are very appealing

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High constitutive investment in carbon-intensive defenses is frequently associated with reduced growth rates or delayed reproduction under low-stress conditions, consistent with classical growthdefense trade-off theory (Herms and Mattson, 1992)