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Beyond hepatic protection, Pue counteracts sarcopenia by remodeling the gut-muscle axis: enhancing gut microbiota diversity, elevating SCFA production, and boosting ATP synthesis to improve skeletal muscle strength (113)

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Consequently, there has been renewed research into concussion and TBI (Sone et al., 2016

This discovery, reported in Cell Metabolism , challenged the traditional view of mitochondria solely as power generators and introduced the concept of bidirectional mitochondrial-nuclear communication