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The functions of the cytosolic GLYR1 and HPR enzymes have been discussed and tested in previous studies

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Scholte, Psychosomatic Medicine 66 (2004) 276282

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The AOD-9604 OPTIONS study: 536 subjects, 24 weeks, and a failed primary endpoint The Phase 2b OPTIONS Study enrolled 536 subjects and ran for 24 weeks, measuring weight loss and body fat reduction as primary and secondary endpoints

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These findings all illustrate that VDAC plays an important role in ferroptosis

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