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In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected

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It undergoes enzymatic conversion to pantothenic acid which is a key component of coenzyme A involved in protein and lipid metabolism

Researchers hypothesized that blocking NNMT activity could represent a novel therapeutic approach, and 5amino1mq emerged as a major outcome of this effort

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The maximum concentration of a drug in the blood after a dose