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Of no less significance are other consequences of obesitychronic kidney disease [23], metabolic dysfunction-associated steatotic liver disease (MASLD) [24], sleep-related breathing disorders with obstructive sleep apnea and obesity hypoventilation syndrome [25], obesity-related cancers (e.g., esophageal or colorectal adenocarcinomas) [26], osteoarthrosis [27] and, last but not least, mental health disorders such as depression or anxiety [28]

However, in the mouse brain, L-carnitine supplementation has been shown to increase brain 5-HT concentration ( 10 , increased low peripheral serotonin values ( Limitations of the study include a relatively small non-randomized retrospective clinical sample

doi:10.1111/j.1360-0443.2011.03461.x

To date, some progress has been made in the fields of functional proteomics and metabolomics