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FIGURE 1 Dopamine Metabolism Selective degeneration of the DA neurons of the SNpc suggests that DA itself may be a source of oxidative stress (Segura-Aguilar et al., 2014)

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Mental Fatigue: NAC and glutathione protect the brain's mitochondria from oxidative damage, ensuring that neurons have the continuous ATP energy required for complex cognitive tasks

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Indeed, the induction of pyroptosis by GSDMD has been shown to protect a melioidosis murine model following infection with the intracellular bacteria, Burkholderia thaliandensis (77)