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doi: 10.1371/journal.ppat.1005238 22 BaluSReljicRLewisMJPleassRJMcIntoshRvan KootenCet al

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The concept of counteracting decreased collagen synthesis and thereby targeting a potential metastatic vulnerability in cancer by using VitC was first proposed by William McCormick over 60 years ago [238, 239], and subsequently extended by Ewan Cameron [240]

It is noteworthy that GSH can also be recruited to the nucleus (e.g

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Several mechanisms have been proposed, including inhibition of free fatty acid release from adipose tissue, increased lipoprotein lipase activity, decreased triglyceride synthesis, decreased VLDL-triglyceride transport, and an inhibition of lipolysis