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Is the outcome a hormone surrogate (GH, IGF-1) or a clinical/imaging endpoint (visceral fat, liver fat)

Gastrointestinal symptoms include a flu-like illness (gastroenteritis) that is characterized by vomiting

Artemisinin activation is decreased in PfK13 mutant lines Artemisinin requires activation by free heme, thus we anticipated that the decrease in heme levels observed in 3-6 hpi ring-stage parasites would result in decreased artemisinin activation and, therefore, decreased activity

2020 Jul/Aug;27(4):246-249

Essentially, your basic metabolic rate and active metabolic rate are the two primary classifications under the larger section of metabolic rate

Proc Natl Acad Sci U S A 100:97859790 Liedschulte V, Wachter A, An ZG, Rausch T (2010) Exploiting plants for glutathione (GSH) production: uncoupling GSH synthesis from cellular controls results in unprecedented GSH accumulation