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These criteria define IBS as recurrent abdominal pain occurring at least once weekly during the past three months, with symptom onset at least six months before diagnosis

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Lagente V, Manoury B, Nenan S, Le QC, Martin-Chouly C, Boichot E: Role of matrix metalloproteinases in the development of airway inflammation and remodeling

2010 Apr;298(4):C961-71

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