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Description

P62 to activate Nrf2 by combining with Keap1, leading to the upregulation of GPX4 and GSH, thereby protecting cells from oxidative stress

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However, the treatment did not significantly blunt the decline in FMD following IR injury in either early or late postmenopausal groups

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moreover, (+)-catechin present in oak inhibited LPS-stimulated NO and TNF- production in macrophages (Guruvayoorappan and Kuttan, 2008)

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doi: 10.7150/thno.96038 288 Heras-SandovalDPrez-RojasJMHernndez-DaminJPedraza-ChaverriJ

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It is concluded that lapatinib has neuroprotective potential against epileptic seizures via suppressing GPX4-mediated ferroptosis

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Portilho et al

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