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These phenomena, in turn, promote the progression of both MASLD and metabolic dysfunction-associated steatohepatitis (MASH)

Elevated levels of tumour necrosis factor (TNF)- , interleukin (IL)-1 and IL-10 in hidradenitis suppurativa skin: a rationale for targeting TNF- and IL-1

The intervertebral disc is a fibrocartilaginous structure situated between two adjacent lumbar vertebrae that serves to enhance spinal mobility, absorb shock, and safeguard the spinal cord

Pro-inflammatory cytokines such as TNF-, IL-1, and IFN- activate NF-B and STAT-1 and 3 pathways, leading to the upregulation of Smad-7 expression (215, 216)

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