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The sediment was then homogenized at 37C for 15 minutes with reagent V after repeated additions of reagent IV

Among these, the abnormal aggregation of -synuclein (-syn) to form Lewy bodies, mitochondrial dysfunction, oxidative stress, impaired protein homeostasis, and neuroinflammation (the activation of microglia and astrocytes leads to the release of various inflammatory factors, such as tumor necrosis factor- (TNF-) and interleukin-1 (IL-1), which exacerbate neuronal damage) constitute the key links in the pathophysiology of PD [6, 7]

The computer-controlled multicompartmental dynamic model of the gastrointestinal system SIMGI

These calves, termed transiently infected (TI), produce antibodies specific to the infecting strain of BVDV and clear the virus prior to birth