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Description

Lentiginous phenotypes caused by diverse pathogenic genes (SASH1 and PTPN11): clinical and molecular discrimination

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The binding efficiency of these peptides was further validated using immunoprecipitation (IP) followed by immunoblotting (IB) in TLR5-overexpressing human intestinal epithelial (Caco-2) cells

Finally, the experimental protocol could also be improved by checking whether lifestyle influences the results, for example by dividing subjects into a physically active and inactive group