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Description

Co-targeting GPCR with glutamine metabolism will likely further inhibit the proliferation of cancer cells, contributing to the anticancer potential and overcoming drug resistance [226]

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In this process, ferroptosis alters the redox status of the tumor microenvironment through the generation of ROS, further influencing the interaction between cancer cells and immune cells

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CYP2E1 and ALDH enzymatic activity CYP2E1 activity was assessed by measuring the rate of oxidation of p -nitrophenol (PNP) to p -nitrocatechol as described 54

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