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Statistical analysis was performed on log-transformed data using Perseus 1.6.2.3 ( (41, 42)

479 The biological functions of m 6 A modification extend beyond its writing (writers) and erasing (erasers) processes

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While these pathways have been extensively elucidated in cancer models, emerging evidence suggests that similar ROS-driven senescenceinflammation feedback loops may play a pathogenic role in chronic metabolic diseases such as T2DM, thereby amplifying tissue dysfunction and insulin resistance ( In recent years, microRNAs (miRNAs) have garnered significant attention for their regulatory roles in mitochondrial homeostasis and ROS scavenging, emerging as critical molecular bridges between mitochondrial dysfunction and insulin resistance

Diurnal variations in plasma concentrations of basic and neutral amino acids and in red cell concentrations of aspartate and glutamate: effects of dietary protein intake

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