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These responses can precede neurodegeneration and are significantly ameliorated in STING-knockout models, indicating that cGASSTING activation plays a pivotal role in -syn-induced neuroinflammation [170, 171]

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HCG protocols, by contrast, carry risks that intensify with duration: electrolyte imbalance, thyroid suppression, and severe rebound weight gain upon discontinuation

In vascular inflammation models, curcumin has been shown to reduce MMP-9 secretion by attenuating ROS production and stabilizing ECM architecture

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TGF- is widely recognized for its potent ability to induce the epithelialmesenchymal transition in various cell types, including hepatocytes