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Another form of renal toxicity, generally associated with NSAIDs, is seen in patients with prerenal conditions leading to the reduction in renal blood flow or blood volume, where the renal prostaglandins have a supportive role in maintaining renal perfusion

Furthermore, both patients received intravenous immunoglobin (IVIG) transfusions, potentially providing cross-reactive antibodies

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Diabetologia 50 , 370379 (2007)