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Mechanistically, this makes sense

Continuous oxidative damage to mtDNA has been linked to aging, inflammation, carcinogenesis, and the development of malignancy [47]

doi: 10.1016/j.phymed.2024.155347 25 HeidarzadehpilehroodR.PirhoushiaranM.AbdollahzadehR.Binti OsmanM.SakinahM.NordinN.et al

Kleeman CR, Tuttle S, Bassett SH

Antibiotic or probiotic aerosolization may alter the lung microbiota, and these changes are related to a reversal of the immunosuppression prevalent in TME [35, 36]