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The liver is a central organ that regulates glucose metabolism by controlling glycogen synthesis and gluconeogenesis

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When these microbiota become imbalanced, a process called "gut dysbiosis" occurs, combined with inflammation of the membrane which lines the intestines -- the gut barrier -- causing "intestinal permeability" or "leaky gut"

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The drug works by activating both GIP and GLP-1 receptors, a dual mechanism that reduces appetite, slows gastric emptying, improves insulin sensitivity, and enhances fat metabolism