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PNPLA3 variant M148 causes resistance to starvation-mediated lipid droplet autophagy in human hepatocytes

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Mutations in DDHD2, encoding an intracellular phospholipase A1, cause a recessive form of complex hereditary spastic paraplegia

Though it is naturally found in foods like fish, meat, and dairy, it is sometimes added to foods, and used in capsule form as a dietary supplement

and wherein at least one of the non-hydrogen substituents at positions R 2 -R 8 is NH 2

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