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Start conservative with a 50-100mg twice-weekly protocol, properly mixed at 50mg/mL concentration for easy measurement

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Though these cancers are not a direct cause of B12 deficiency, B12 deficiency may be an initial presenting sign of an underlying malignancy when no other reason can be determined

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MRI spinal cord revealed hyperintense signal on T2-weighted image in thoracic spinal cord from T2T8 segments and on axial T2-weighted section showed posterior column hyperintense signal making classical inverted V sign, which is a characteristic finding of vitamin B12 deficiency

Pernicious anaemia - the leading cause of B12 deficiency in the UK - is an autoimmune condition whereby your immune system attacks the cells in your stomach that produce intrinsic factor - a protein that your body uses to absorb vitamin B12