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Key Research Applications Telomere elongation: Epitalon activates telomerase reverse transcriptase (hTERT), enabling DNA telomere elongation in human somatic cells and counteracting the Hayflick limit of replicative senescence

Allow it to air dry for ten seconds

In senescent cells, this selectively causes p53 nuclear exclusion and cell-intrinsic apoptosis

surrogate endpoints (weight, HbA1c) are not hard outcomes

(A) The structure of hepatocyte growth factor (HGF) includes a -chain (69 kDa) of four Kringle domains and a -chain (43 kDa) consisting of a serine proteinase homology (SPH) domain linked by disulfide bonds