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Through the precise regulation of carnitine levels, new treatments can be developed for these complex diseases, and more effective interventions can be provided for patients (Fig

Metabolites were quantified by LC-MS/MS

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A previous meta-analysis by Lynch et al.[15] including 4 RCTs (145 participants) reporting dialysis-related hypotension and 6 RCTs (149 participants) reporting muscle cramps failed to demonstrate benefits for preventing either dialysis-related hypotension or muscle cramps among hemodialysis patients